| Catalog No. | Size | Price (USD) |
| rp152261-10μg | 10μg | $139.90 |
| rp152261-50μg | 50μg | $499.90 |
| rp152261-100μg | 100μg | $899.90 |
| rp152261-1mg | 1mg | $4,499.90 |
Product Information
| Product Name | Recombinant Human TGF-beta 1 Protein |
| Short Description | Animal Free, ≥95% (SDS-PAGE), Active, 293F, N-8*His tag, 30-390 aa (C33S) |
| Species | Human |
| Expressed Host | HEK293 |
| Accession | P01137 |
| Amino Acids | 30-390 aa (C33S) |
| Form | Lyophilized |
| Purity | ≥95% (SDS-PAGE) |
| Specifications & Purity | Animal Free,Carrier Free,Bioactive,ActiBioPure™,High Performance,His-Tag,≥95%(SDS-PAGE) |
| Endotoxin Concentration | <0.1 EU/μg |
| Biological Activity | 1、Measured by its ability to inhibit the IL-4-dependent proliferation of TF‑1 human erythroleukemic cells. The ED50 for this effect is 0.34 ng/mL in the presence of the 2.0 ng/mL Recombinant Mouse IL-4 Protein (rp154228). 2、Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. The ED50 for this effect is 35.9 ng/mL. |
| SDS Page | 13 & 42 & 55 kDa, under reducing conditions; 26 & 84 & 110 kDa, under non-reducing conditions. |
| Sequence | HHHHHHHHLSTSKTIDMELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWRYLSNRLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSRDNTLQVDINGFTTGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS |
| Synonyms | Cartilage-inducing factor | CED | Differentiation inhibiting factor | DPD1 | LAP | Latency-associated peptide | Prepro transforming growth factor beta 1 | TGF beta | TGF beta 1 | TGF beta 1 protein | TGF-beta 1 protein | TGF-beta-1 | TGF-beta-5 | TGF-beta |
Product Description
Function
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
Reconstitution
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage and Shipping
| Shipped In | Ice chest + Ice pads |
| Stability and Storage | Store at -20~-80℃ for more than 1 year. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
