| Catalog No. | Size | Price (USD) |
| rp151390-10μg | 10μg | $139.90 |
| rp151390-50μg | 50μg | $479.90 |
| rp151390-100μg | 100μg | $769.90 |
| rp151390-1mg | 1mg | $4,939.90 |
Product Information
| Product Name | Recombinant Human Semaphorin 3C Protein |
| Short Description | Animal Free, ≥95% (SDS-PAGE), Active, HEK293, C-His, 21-738 aa (R551A, R552A, R611A, R612A) |
| Species | Human |
| Expressed Host | HEK293 |
| Accession | Q99985-1 |
| Amino Acids | 21-738 aa (R551A, R552A, R611A, R612A) |
| Protein TAG | C-hFc |
| Form | Lyophilized |
| Specifications & Purity | Animal Free,Carrier Free,Bioactive,ActiBioPure™,High Performance,His-Tag,≥95%(SDS-PAGE) |
| Endotoxin Concentration | <0.1 EU/μg |
| Biological Activity | Measured by the ability of the immobilized protein to support the adhesion of SVEC4 10 mouse vascular endothelial cells to Fibronectin. Recombinant Human (rh) Semaphorin 3C immobilized at 10 μg/mL, with 2 ng/mL rhFN-1, 100 μL/well, will induce approximately 50-75% adhesion. |
| SDS Page | 82 kDa, under reducing conditions. |
| Sequence | GSSQPQARVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSAAQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDAAKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGDESQKMRGDYGKLKALINSHHHHHH |
| Synonyms | Sema E | Semaphorin-E | (semaphorin) 3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted | Sema E | SEMA3C | SEMAE | Semaphorin 3C | Semaphorin E | semaphorin-3C | semaphorin-E | SEME | SemE | (semaphorin) 3C | sema domain, immunogl |
Product Description
Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance.
Reconstitution
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
Storage and Shipping
| Shipped In | Ice chest + Ice pads |
| Stability and Storage | Store at -20~-80℃ long term (1 year). Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
Additional Information
| Protein Construction | Disulfide-linked homodimer |
