Mouse thymus activation regulated chemokine,TARC ELISA Kit CSB-E14144m CUSABIO
$50.00
In stock
SKU
CSB-E14144m
Product Details
| Target Name | thymus activation regulated chemokine,TARC |
| Species | Mus musculus (Mouse) |
| Storage | Store at 2-8°C. Please refer to protocol. |
| Sensitivity | 10.512 pg/mL |
| Troubleshooting and FAQs | ELISA kit FAQs |
| Lead Time | 3-5 working days after you place the order, and it takes another 3-5 days for delivery via DHL or FedEx. |
| Abbreviation | TARC/CCL17 |
| Sample Types | serum, plasma, cell culture supernates, tissue homogenates |
| Detection Range | 31.25 pg/mL-2000 pg/mL |
| Assay Time | 1-5h |
| Sample Loading Volume | 50-100ul |
| Detection Wavelength | 450 nm |
| Research Area | Immunology |
| Assay Principle | quantitative |
| Measurement | Sandwich |
| ELISA Data Analysis | ELISA Standard Curve & Curve Expert software |
| Shelf Life | 6 months |
| Description | The product CSB-E14144m is a sandwich ELISA kit developed to measure levels of mouse thymus activation regulated chemokine (TARC) in multiple samples, including serum, plasma, cell culture supernates, or tissue homogenates. The enzyme-substrate chromogenic reaction is also used to amplify the signal and quantify the levels of the analyte through the intensity of the colored product. The color intensity positively correlates with the amount of TARC bound in the initial step. TRAC, also called CCL17, is a chemokine responsible for trafficking Th2 cells into sites of allergic inflammation. It promotes chemotaxis of effector T cells and supports DC-T cell interactions as well as DC migration towards TRAC-ligands. TARC binds specifically to CCR4 with high affinity and is involved in the trafficking of Th2 cells in eosinophil-associated disorders, including AA and AD, and presumably of neoplastic cells in certain T cell lymphomas such as angioimmunoblastic T cell lymphoma (AITL), mycosis fungoides (MF), and Sezary syndrome (SS). Lorenz Fülle et al. proved that TARC exerts a neuroimmune modulatory function and is expressed in hippocampal neurons through mouse models. |
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