Elab Fluor ® 647 Anti-Mouse CD8a Antibody[53-6.7] (E-AB-F1104UM) elabscience
$190.00
In stock
SKU
E-AB-F1104UM
| Size | Price (USD) |
| 100μg | $190.00 |
| 25μg | $80.00 |
Product Details
| Abbre | CD8a |
| Synonyms | CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2 |
| Swissprot | P01731 |
| Reactivity | Mouse |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 53-6.7 |
| Isotype | Rat IgG2a, κ |
| Isotype Control | Elab Fluor ® 647 Rat IgG2a, κ Isotype Control[2A3] |
| Applications | FCM |
| Conjugation | Elab Fluor ® 647 |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: Elab Fluor ® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter).
Background: CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
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