CYCS Monoclonal Antibody (E-AB-22110) elabscience
$399.00
In stock
SKU
E-AB-22110
| Size | Price (USD) |
| 200μL | $399.00 |
| 120μL | $240.00 |
| 60μL | $143.00 |
| 20μL | $73.00 |
Product Details
| Abbre | CYCS |
| Synonyms | CYC, CYCS, Cytochrome c, Cytochrome c somatic, HCS, THC4 |
| Swissprot | P99999 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 8G3 |
| Isotype | IgG |
| Applications | WB, IHC-p, IF |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Immunogen | Recombinant Protein |
| Observed MW | 14 kDa The actual band is not consistent with the expectation. Western blotting is a method for detecting a certain protein in a complex sample based on the specific binding of antigen and antibody. Different proteins can be divided into bands based on different mobility rates. The mobility is affected by many factors, which may cause the observed band size to be inconsistent with the expected size. The common factors include: 1. Post-translational modifications: For example, modifications such as glycosylation, phosphorylation, methylation, and acetylation will increase the molecular weight of the protein. 2. Splicing variants: Different expression patterns of various mRNA splicing bodies may produce proteins of different sizes. 3. Post-translational cleavage: Many proteins are first synthesized into precursor proteins and then cleaved to form active forms, such as COL1A1. 4. Relative charge: the composition of amino acids (the proportion of charged amino acids and uncharged amino acids). 5. Formation of multimers: For example, in protein dimer, strong interactions between proteins can cause the bands to be larger. However, the use of reducing conditions can usually avoid the formation of multimers. If a protein in a sample has different modified forms at the same time, multiple bands may be detected on the membrane. |
| Research Areas | Cancer, Cell Biology, Cardiovascular, Metabolism, Signal Transduction |
| Cellular Localization | Mitochondrion matrix. |
Product Description
Background: This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome.
Storage and Shipping
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Additional Information
| Verified Samples | Verified Samples in WB: Hela, 293T, 3T3, Mouse liver, Rat liver, Rat kidney Verified Samples in IHC: Mouse kidney Verified Samples in IF: Rat liver |
| Dilution | WB 1:500-1:2000, IHC 1:100-1:300, IF 1:100-1:300 |
- Phosphocreatine Mitigates Doxorubicin-Induced Neurotoxicity in Rats by Regulating Mitochondrial Function and Apoptosis via the NF-κB/PGC-1α Pathway
Journal: NEUROMOLECULAR MEDICINE | Year: 2025 | Impact Factor: 3.900
DOI: 10.1007/s12017-025-08872-y | Reactivity: Rat | Sample Type: brain tissue - Potential anti-liver cancer targets and mechanisms of kaempferitrin based on network pharmacology, molecular docking and experimental verification
Journal: COMPUTERS IN BIOLOGY AND MEDICINE | Year: 2024 | Impact Factor: 7.000
DOI: 10.1016/j.compbiomed.2024.108693 | Reactivity: Mouse, Human | Sample Type: SMMC-7721 cell-Xenograft, SMMC-7721 cell - Phosphocreatine attenuates doxorubicin-induced nephrotoxicity through inhibition of apoptosis, and restore mitochondrial function via activation of Nrf2 and PGC-1α pathways
Journal: CHEMICO-BIOLOGICAL INTERACTIONS | Year: 2024 | Impact Factor: 4.700
DOI: 10.1016/j.cbi.2024.111147 | Reactivity: Rat | Sample Type: kidney tissue - Curcumin and gallic acid have a synergistic protective effect against ovarian surface epithelium and follicle reserve damage caused by autologous intraperitoneal ovary transplantation in rats
Journal: PATHOLOGY RESEARCH AND PRACTICE | Year: 2024 | Impact Factor: 2.900
DOI: 10.1016/j.prp.2024.155320 | Reactivity: Rat | Sample Type: ovarian tissue
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