E-Selectin Polyclonal Antibody (E-AB-14325) elabscience
$399.00
In stock
SKU
E-AB-14325
200μL $ 399.00
Product Details
| Abbre | E-Selectin |
| Synonyms | CD26E, CD62 antigen-like family member E, CD62E, E selectin, E-selectin, ELAM, ELAM-1, ELAM1, ESEL, Endothelial adhesion molecule 1, Endothelial leukocyte adhesion molecule 1, LECAM2, LYAM2, Leukocyte-endothelial cell adhesion molecule 2, Sele, Selectin E |
| Swissprot | P16581 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | IHC |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Immunogen | Recombinant protein of human SELE |
| Research Areas | Cancer, Cardiovascular, Immunology, Stem Cells |
| Cellular Localization | Membrane. |
Product Description
Background: The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
Storage and Shipping
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Additional Information
| Verified Samples | Verified Samples in IHC: Human esophagus cancer, Human lung cancer |
| Dilution | IHC 1:50-1:200 |
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