ERAS Polyclonal Antibody (E-AB-13219) elabscience
$399.00
In stock
SKU
E-AB-13219
200μL $ 399.00
Product Details
| Abbre | ERAS |
| Synonyms | E ras, E-Ras, ES cell expressed Ras, Embryonic stem cell expressed Ras, Embryonic stem cell-expressed Ras, Eras, GTPase ERas, HRAS2, HRASP, Ha-Ras2, MGC126691, MGC126693, OTTHUMP00000065857, RASE, Small GTPase protein E Ras, ecat5, v Ha ras Harvey rat sarcoma viral oncog |
| Swissprot | Q7Z444 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | WB, IHC |
| Conjugation | Unconjugated |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Immunogen | Synthetic peptide of human ERAS |
| Calculated MW | 25 kDa |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Developmental Biology, Signal Transduction, Stem Cells |
| Cellular Localization | Cell membrane. |
Product Description
Background: This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance.
Storage and Shipping
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Additional Information
| Verified Samples | Verified Samples in WB: Mouse heart Verified Samples in IHC: Human thyroid cancer, Human ovarian cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
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