FANCE Polyclonal Antibody (E-AB-17948) elabscience

$399.00
In stock
SKU
E-AB-17948
200μL $ 399.00

Product Details

AbbreFANCE
Synonyms2810451D06Rik , AI415634, AW209126, FACE, FAE, FANCE, Fanconi anemia complementation group E, Fanconi anemia group E protein, OTTHUMP00000016254, Protein FACE, RGD1561045
SwissprotQ9HB96
ReactivityHuman
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ApplicationsIHC
ConjugationUnconjugated
Concentration1.5 mg/mL
BufferPhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification MethodAntigen affinity purification
ImmunogenSynthetic peptide of human FANCE
Research AreasEpigenetics and Nuclear Signaling
Cellular LocalizationNucleus.

Product Description

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E.

Storage and Shipping

StorageStore at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
ShippingThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Additional Information

Verified SamplesVerified Samples in IHC: Human thyroid cancer
DilutionIHC 1:40-1:200

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