MMP1 Polyclonal Antibody (E-AB-10061) elabscience
$399.00
In stock
SKU
E-AB-10061
| Size | Price (USD) |
| 200μL | $399.00 |
| 120μL | $240.00 |
| 60μL | $143.00 |
| 20μL | $73.00 |
Product Details
| Abbre | MMP1 |
| Synonyms | 27 kDa interstitial collagenase, CLG, CLGN, Fibroblast collagenase, Interstitial collagenase, Matrix Metalloproteinase 1, Matrix metall, Matrix metallopeptidase 1 (interstitial collagenase), Matrix metalloprotease 1, collagenase, fibroblast, interstitial |
| Swissprot | P03956 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | IHC |
| Conjugation | Unconjugated |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Immunogen | Recombinant protein of human MMP1 |
| Research Areas | Cancer, Cell Biology, Cardiovascular, Signal Transduction |
| Cellular Localization | Secreted>extracellular space>extracellular matrix. |
Product Description
Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
Storage and Shipping
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Additional Information
| Verified Samples | Verified Samples in IHC: Human cervical cancer, Human lung cancer |
| Dilution | IHC 1:50-1:200 |
- ACY-1215 exhibits anti-inflammatory and chondroprotective effects in human osteoarthritis chondrocytes via inhibition of STAT3 and NF-κB signaling pathways
Journal: BIOMEDICINE & PHARMACOTHERAPY | Year: 2018 | Impact Factor: 3.457
DOI: 10.1016/j.biopha.2018.11.017 | Reactivity: human | Sample Type: Cell culture supernatant
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