PAFAH1B3 Polyclonal Antibody (E-AB-53102) elabscience

$399.00
In stock
SKU
E-AB-53102
SizePrice (USD)
200μL$399.00
120μL$240.00
60μL$143.00
20μL$73.00

Product Details

AbbrePAFAH1B3
SynonymsPA1B3, PAF AH 29 kDa subunit, PAF AH subunit gamma, PAF acetylhydrolase 29 kDa subunit, PAF-AH 29 kDa subunit, PAF-AH subunit gamma, PAFAH subunit gamma, PAFAHG, Pafah1b3, Platelet activating factor acety, Platelet activating factor acetylhydrolase IB subunit gamma
SwissprotQ15102
ReactivityHuman, Mouse, Rat
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ApplicationsIHC
ConjugationUnconjugated
Concentration1.02 mg/mL
BufferPhosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification MethodAntigen affinity purification
ImmunogenFusion protein of human PAFAH1B3
Research AreasCardiovascular, Metabolism, Neuroscience, Signal transduction
Cellular LocalizationCytoplasm.

Product Description

Background: This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with cognitive disability, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described.

Storage and Shipping

StorageStore at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
ShippingThe product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Additional Information

Verified SamplesVerified Samples in IHC: Human colorectal cancer
DilutionIHC 1:50-1:200

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