Elab Fluor ® Violet 450 Anti-Rat CD45 Antibody[OX-1] (E-AB-F1227Q) elabscience

$90.00
In stock
SKU
E-AB-F1227Q
SizePrice (USD)
100Tests$90.00
50Tests$60.00
100Tests×2$162.00

Product Details

AbbreCD45
SynonymsLCALy-5T200, Leukocyte common antigen, Ptprc, Receptor-type tyrosine-protein phosphatase C
SwissprotP04157
ReactivityRat
HostMouse
ClonalityMonoclonal
CloneOX-1
IsotypeMouse IgG1, κ
Isotype ControlElab Fluor ® Violet 450 Mouse IgG1, κ Isotype Control[MOPC-21]
ApplicationsFCM
ConjugationElab Fluor ® Violet 450
Concentration5 μL/Test
BufferPhosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research AreasCell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers
Cellular LocalizationMembrane

Product Description

Conjugation Information: Elab Fluor ® Violet 450 is designed to be excited by the violet laser (405 nm) and detected using an optical filter centered near 450 nm (e.g., a 450/45 nm bandpass filter).

Background: CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.

Storage and Shipping

StorageThis product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
ShippingIce bag
  1. NAD+/Nrf2 signaling promotes osteogenesis by regulating oxidative level of BMSCs under mechanical stress
    Journal: Progress in Orthodontics | Year: 2025 | Impact Factor: 3.500
    DOI: 10.1186/s40510-025-00566-2 | Reactivity: Rat | Sample Type: bone marrow mesenchymal stem cells (BMSCs)
  2. Exosomes derived from TGF-β1-pretreated mesenchymal stem cells alleviate biliary ischemia–reperfusion injury through Jagged1/Notch1/SOX9 pathway
    Journal: INTERNATIONAL IMMUNOPHARMACOLOGY | Year: 2023 | Impact Factor: 5.600
    DOI: 10.1016/j.intimp.2023.110253 | Reactivity: Rat | Sample Type: mesenchymal stem cells(MSCs)
  3. Mechanical Force Modulates Alveolar Bone Marrow Mesenchymal Cells Characteristics for Bone Remodeling during Orthodontic Tooth Movement through Lactate Production
    Journal: Cells | Year: 2022 | Impact Factor: 7.666
    DOI: 10.3390/cells11233724 | Reactivity: Rat
  4. CHNQD-00603 Promotes Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells by the miR-452-3p-Mediated Autophagy Pathway.
    Journal: Frontiers in Cell and Developmental Biology | Year: 2021 | Impact Factor: 6.684
    DOI: 10.3389/fcell.2021.779287 | Reactivity: Rat | Sample Type: BMSC

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