SNCA Polyclonal Antibody (E-AB-13070) elabscience
$399.00
In stock
SKU
E-AB-13070
| Size | Price (USD) |
| 200μL | $399.00 |
| 120μL | $240.00 |
| 60μL | $143.00 |
| 20μL | $73.00 |
Product Details
| Abbre | SNCA |
| Synonyms | Alpha synuclein, Alpha-synuclein, MGC105443, MGC110988, MGC127560, MGC64356, NACP, No, Non A beta component of AD amyloid, Non A4 component of amyloid, Non A4 component of amyloid precursor, Non-A beta component of AD amyloid, alphaSYN, isoform NACP140 |
| Swissprot | P37840 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | IHC |
| Conjugation | Unconjugated |
| Concentration | 0.1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Immunogen | Synthetic peptide of human SNCA |
| Research Areas | Cancer, Neuroscience |
| Cellular Localization | Cytoplasm, cytosol. Membrane. Nucleus. Cell junction, synapse. Secreted. Membrane-bound in dopaminergic neurons. |
Product Description
Background: Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
Storage and Shipping
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Additional Information
| Verified Samples | Verified Samples in IHC: Human brain, Human thyroid cancer |
| Dilution | IHC 1:25-1:100 |
- Cajanus cajan (L) Millsp seeds extract prevents rotenone-induced motor- and non-motor features of Parkinson disease in mice: Insight into mechanisms of neuroprotection
Journal: JOURNAL OF ETHNOPHARMACOLOGY | Year: 2023 | Impact Factor: 5.400
DOI: 10.1016/j.jep.2023.117623 | Reactivity: Mouse | Sample Type: striatum tissue
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