FITC Anti-Human CD11b Antibody[ICRF44] (E-AB-F1146C) elabscience
$90.00
In stock
SKU
E-AB-F1146C
| Size | Price (USD) |
| 100Tests | $90.00 |
| 20Tests | $30.00 |
| 100Tests×2 | $156.00 |
Product Details
| Abbre | CD11b |
| Synonyms | CD11 antigen-like family member B, CD11b, CR-3 alpha chain, Integrin alpha-M, Itgam, Leukocyte adhesion receptor MO1 |
| Swissprot | P11215 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ICRF44 |
| Isotype | Mouse IgG1, κ |
| Isotype Control | FITC Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications | FCM |
| Conjugation | FITC |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Background: CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
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