FITC Anti-Human CD206/MMR Antibody[15-2] (E-AB-F1161C) elabscience
| Size | Price (USD) |
| 100Tests | $190.00 |
| 20Tests | $75.00 |
| 100Tests×2 | $285.00 |
| Size | Price (USD) |
| 100Tests | $190.00 |
| 20Tests | $75.00 |
| 100Tests×2 | $285.00 |
Product Details
| Abbre | CD206 |
| Synonyms | CLEC13D, CLEC13DL, MMR, MRC1L1, hMR |
| Swissprot | P22897 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 15-2 |
| Isotype | Mouse IgG1, κ |
| Isotype Control | FITC Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications | FCM |
| Conjugation | FITC |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Biology, Immunology, Neuroscience, Neuroscience Cell Markers |
| Cellular Localization | Membrane;Endosome |
Product Description
Conjugation Information: FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Background: Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known as CD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) that belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, and hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates endocytosis and phagocytosis, induces activation of macrophages and antigen presentation, plays an important role in host defense, and provides a link between innate and adaptive immunity.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |