FITC Anti-Human CD206/MMR Antibody[15-2] (E-AB-F1161C) elabscience

$190.00
In stock
SKU
E-AB-F1161C
SizePrice (USD)
100Tests$190.00
20Tests$75.00
100Tests×2$285.00

Product Details

AbbreCD206
SynonymsCLEC13D, CLEC13DL, MMR, MRC1L1, hMR
SwissprotP22897
ReactivityHuman
HostMouse
ClonalityMonoclonal
Clone15-2
IsotypeMouse IgG1, κ
Isotype ControlFITC Mouse IgG1, κ Isotype Control[MOPC-21]
ApplicationsFCM
ConjugationFITC
Concentration5 μL/Test
BufferPhosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research AreasCell Biology, Immunology, Neuroscience, Neuroscience Cell Markers
Cellular LocalizationMembrane;Endosome

Product Description

Conjugation Information: FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).

Background: Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known as CD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) that belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, and hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates endocytosis and phagocytosis, induces activation of macrophages and antigen presentation, plays an important role in host defense, and provides a link between innate and adaptive immunity.

Storage and Shipping

StorageThis product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
ShippingIce bag
  1. MTFR2 promotes VDAC1 oligomerization to reprogram BCAA metabolism in tumor cells to polarize TAMs in LUAD
    Journal: Cell Death & Disease | Year: 2026 | Impact Factor: 12.200
    DOI: 10.1038/s41419-026-08871-2 | Reactivity: Human | Sample Type: THP-1 cell
  2. ILF2 cooperates with ILF3/KLF16 to drive colorectal cancer progression via modulating the behaviors of both tumor cells and M2 macrophages
    Journal: APOPTOSIS | Year: 2026 | Impact Factor: 8.100
    DOI: 10.1007/s10495-026-02259-5 | Reactivity: Human, Mouse
  3. ADH4 deficiency activates the NRF2-CSF1 axis by increased lipid peroxidation in hepatocellular carcinoma
    Journal: Cancer Cell International | Year: 2026 | Impact Factor: 7.000
    DOI: 10.1186/s12935-025-03940-6 | Reactivity: Human | Sample Type: THP1 cell
  4. Hepatitis B virus promotes hepatocellular carcinogenesis by activating IL-6-dependent tumor-macrophage crosstalk and M2-like macrophage polarization
    Journal: JOURNAL OF BIOLOGICAL CHEMISTRY | Year: 2026 | Impact Factor: 4.100
    DOI: 10.1016/j.jbc.2026.113283 | Reactivity: Human, Mouse
  5. RBMS1 enhances PDPK1 mRNA stability to promote multiple myeloma malignancy and M2 macrophage polarization
    Journal: CELL CYCLE | Year: 2026 | Impact Factor: 3.900
    DOI: 10.1080/15384101.2026.2686804 | Reactivity: Mouse, Human | Sample Type: bone marrow tissue, mouse bone marrow cell
  6. HMGA2 promotes hepatocellular carcinoma progression by regulating tumor-associated macrophage via Notch1/CCL2 signaling
    Journal: MOLECULAR AND CELLULAR BIOCHEMISTRY | Year: 2026 | Impact Factor: 3.700
    DOI: 10.1007/s11010-026-05491-4 | Reactivity: Human | Sample Type: HepG2 cell
  7. Mycobacterium tuberculosis escapes immunity by regulating FUS/TLR4 and metabolic reprogramming to suppress macrophage activity
    Journal: Journal of Radiation Research and Applied Sciences | Year: 2026 | Impact Factor: 2.500
    DOI: 10.1016/j.jrras.2026.102285 | Reactivity: Human | Sample Type: THP-1 cell
  8. Additive Manufactured Magnetoelectric Wireless Retainer as the Periodontal Remodeler for Post-Orthodontic Tissue Reconstruction and Relapse-Inhibition
    Journal: Advanced Science | Year: 2025 | Impact Factor: 14.100
    DOI: 10.1002/advs.202505020 | Reactivity: Human | Sample Type: macrophage
  9. SEMA7A orchestrates the colorectal cancer tumor microenvironment via PlexinC1: coordinating angiogenesis and macrophage M2 polarization
    Journal: BIOCHEMICAL PHARMACOLOGY | Year: 2025 | Impact Factor: 5.600
    DOI: 10.1016/j.bcp.2025.117638 | Reactivity: Human | Sample Type: THP1 cell
  10. Defining gastric cancer ecology: the crucial roles of TREM2+ macrophages and fibroblasts in tumor microenvironments
    Journal: Communications Biology | Year: 2025 | Impact Factor: 5.200
    DOI: 10.1038/s42003-025-07512-2 | Reactivity: Human | Sample Type: macrophages
  11. SLC16A3 in lung adenocarcinoma regulates glycolysis and lactate release to facilitate M2 polarization of tumor-associated macrophages
    Journal: CANCER IMMUNOLOGY IMMUNOTHERAPY | Year: 2025 | Impact Factor: 5.100
    DOI: 10.1007/s00262-025-04264-0 | Reactivity: Human, Mouse | Sample Type: H1693 cell
  12. Molecular mechanism of the combined exposure to AFB1 and DON in promoting the functional and phenotypic remodeling of porcine alveolar macrophages
    Journal: FOOD AND CHEMICAL TOXICOLOGY | Year: 2025 | Impact Factor: 3.500
    DOI: 10.1016/j.fct.2025.115686 | Reactivity: Porcine
  13. Cedrol impedes lung cancer metastasis by reducing tumor-associated macrophage polarization mediated by MYC-driven aerobic glycolysis
    Journal: Human Cell | Year: 2025 | Impact Factor: 3.100
    DOI: 10.1007/s13577-025-01299-4 | Reactivity: Human | Sample Type: A549 cell,H1299 cell
  14. Macrophage M2 polarization induced by ANKRD22 in lung adenocarcinoma facilitates tumor angiogenesis
    Journal: Central European Journal of Immunology | Year: 2025 | Impact Factor: 1.500
    DOI: 10.5114/ceji.2025.149372 | Reactivity: Human | Sample Type: A549 cell
  15. Cinobufagin modulates vasculogenic mimicry and tumor-associated macrophages to inhibit ovarian cancer progression
    Journal: EUROPEAN JOURNAL OF PHARMACOLOGY | Year: 2024 | Impact Factor: 4.200
    DOI: 10.1016/j.ejphar.2024.177157 | Reactivity: Human | Sample Type: THP-1 cell
  16. Zingerone enhances the antitumor activity of attenuated Salmonella-mediated cancer immunotherapy by promoting tumor infiltration by host immune cells
    Journal: Journal of Functional Foods | Year: 2024 | Impact Factor: 3.800
    DOI: 10.1016/j.jff.2024.106017 | Reactivity: Mouse | Sample Type: CT-26 cell-Xenograft cell
  17. 15-Deoxy-Δ-12,14-Prostaglandin J2 Represses Immune Escape of Lung Adenocarcinoma by Polarizing Macrophages Through Epidermal Growth Factor Receptor/Ras/Raf Pathway
    Journal: JOURNAL OF IMMUNOTHERAPY | Year: 2024 | Impact Factor: 3.200
    DOI: 10.1097/CJI.0000000000000546 | Reactivity: Human | Sample Type: A549 cell,CD8+ T cell,macrophage
  18. SNHG12 in cancer-associated fibroblast-derived extracellular vesicle induces macrophage-myofibroblast transition
    Journal: Epigenomics | Year: 2024 | Impact Factor: 3.000
    DOI: 10.1080/17501911.2024.2430166 | Reactivity: Human | Sample Type: THP-1 cell
  19. Anti-tumor effect of AZD8055 against bladder cancer and bladder cancer-associated macrophages
    Journal: Heliyon | Year: 2023 | Impact Factor: 4.000
    DOI: 10.1016/j.heliyon.2023.e14272 | Reactivity: Human

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