Transferrin Monoclonal Antibody (E-AB-22082) elabscience
$399.00
In stock
SKU
E-AB-22082
| Size | Price (USD) |
| 200μL | $399.00 |
| 120μL | $240.00 |
| 60μL | $143.00 |
| 20μL | $73.00 |
Product Details
| Abbre | Transferrin |
| Synonyms | Apotransferrin, Beta 1 metal binding globulin, Beta-1 metal-binding globulin, DKFZp781D0156, PRO1400, PRO1557, PRO2086, Serotransferrin, Serotransferrin precursor, Siderophilin, TF, TFQTL1, TRFE, Transferin, Transferrin |
| Swissprot | P02787 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 9B3 |
| Isotype | IgG |
| Applications | WB, IHC-p, IF |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Protein A purification |
| Immunogen | Synthetic Peptide |
| Observed MW | 77 kDa The actual band is not consistent with the expectation. Western blotting is a method for detecting a certain protein in a complex sample based on the specific binding of antigen and antibody. Different proteins can be divided into bands based on different mobility rates. The mobility is affected by many factors, which may cause the observed band size to be inconsistent with the expected size. The common factors include: 1. Post-translational modifications: For example, modifications such as glycosylation, phosphorylation, methylation, and acetylation will increase the molecular weight of the protein. 2. Splicing variants: Different expression patterns of various mRNA splicing bodies may produce proteins of different sizes. 3. Post-translational cleavage: Many proteins are first synthesized into precursor proteins and then cleaved to form active forms, such as COL1A1. 4. Relative charge: the composition of amino acids (the proportion of charged amino acids and uncharged amino acids). 5. Formation of multimers: For example, in protein dimer, strong interactions between proteins can cause the bands to be larger. However, the use of reducing conditions can usually avoid the formation of multimers. If a protein in a sample has different modified forms at the same time, multiple bands may be detected on the membrane. |
| Research Areas | Cancer, Cardiovascular, Metabolism, Signal Transduction |
| Cellular Localization | Secreted. |
Product Description
Tissue Specificity: Expressed by the liver and secreted in plasma
Background: This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum.
Storage and Shipping
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Additional Information
| Verified Samples | Verified Samples in WB: Human serum Verified Samples in IHC: Human liver Verified Samples in IF: Human lung cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:300, IF 1:100-1:300 |
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