FITC Anti-Mouse Ly6A/E(Sca-1) Antibody[D7] (E-AB-F1191UC) elabscience
$115.00
In stock
SKU
E-AB-F1191UC
| Size | Price (USD) |
| 100μg | $115.00 |
| 25μg | $35.00 |
Product Details
| Abbre | Ly-6A/E |
| Synonyms | Ly-6A.2/Ly-6E.1, Ly6, Ly6a, SCA-1, TAP |
| Swissprot | P05533 |
| Reactivity | Mouse |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | D7 |
| Isotype | Rat IgG2a, κ |
| Isotype Control | FITC Rat IgG2a, κ Isotype Control[2A3] |
| Applications | FCM |
| Conjugation | FITC |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Immunology, Stem Cells |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Background: Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
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