PE Anti-Human CD11b Antibody[HI11b] (E-AB-F1317D) elabscience

$90.00
In stock
SKU
E-AB-F1317D
SizePrice (USD)
100Tests$90.00
20Tests$30.00
100Tests×2$150.00

Product Details

AbbreCD11b
SwissprotP11215
ReactivityHuman
HostMouse
ClonalityMonoclonal
CloneHI11b
IsotypeMouse IgG2b, κ
Isotype ControlPE Mouse IgG2b, κ Isotype Control[MPC-11]
ApplicationsFCM
ConjugationPE
Concentration5 μL/Test
BufferPhosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Cellular LocalizationMembrane

Product Description

Conjugation Information: PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).

Background: CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.

Storage and Shipping

StorageThis product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
ShippingIce bag
  1. Clofibrate inhibits tumor immune escape by increasing macrophage phagocytosis
    Journal: EUROPEAN JOURNAL OF PHARMACOLOGY | Year: 2026 | Impact Factor: 4.700
    DOI: 10.1016/j.ejphar.2026.178825 | Reactivity: Human | Sample Type: THP-1 cell
  2. Metformin suppresses PPARδ-driven CD47 transcription to enhance macrophage phagocytosis in lung cancer
    Journal: JOURNAL OF BIOLOGICAL CHEMISTRY | Year: 2026 | Impact Factor: 3.900
    DOI: 10.1016/j.jbc.2026.111159 | Reactivity: Human, Mouse | Sample Type: H1975 cell,H1299 cell,H520 cell,THP-1 cell
  3. Anti-inflammatory effects of 1,7-dihydroxy-3,4-dimethoxyxanthone through inhibition of M1-phenotype macrophages via arginine/mitochondrial axis
    Journal: IMMUNOLOGIC RESEARCH | Year: 2024 | Impact Factor: 3.300
    DOI: 10.1007/s12026-024-09538-w | Reactivity: Human | Sample Type: THP-1 cell

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