PE Anti-Human CD80 Antibody[2D10] (E-AB-F1232D) elabscience
$170.00
In stock
SKU
E-AB-F1232D
| Size | Price (USD) |
| 100Tests | $170.00 |
| 20Tests | $66.00 |
| 100Tests×2 | $260.00 |
Product Details
| Abbre | CD80 |
| Synonyms | B7BB1, B7-1, T-lymphocyte activation antigen CD80 |
| Swissprot | P33681 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 2D10 |
| Isotype | Mouse IgG1, κ |
| Isotype Control | PE Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications | FCM |
| Conjugation | PE |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Immunology, Innate Immunity |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Background: CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
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DOI: 10.1155/2022/3946754 | Reactivity: Human | Sample Type: PBMCs
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