PE Anti-Human CD8a Antibody[HIT8a] (E-AB-F1271D) elabscience
$60.00
In stock
SKU
E-AB-F1271D
| Size | Price (USD) |
| 100Tests | $60.00 |
| 20Tests | $20.00 |
| 100Tests×2 | $100.00 |
Product Details
| Abbre | CD8a |
| Synonyms | CD8Leu-2Ly-2, CD8, CD8 antigen alpha po, CD8 antigen alpha polypeptide, CD8A, Leu, Leu2, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu, T-lymphocyte differentiation antigen T8/Leu-2, T8, alpha polypeptide (p32), p32 |
| Swissprot | P01732 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | HIT8a |
| Isotype | Mouse IgG1, κ |
| Isotype Control | PE Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications | FCM |
| Conjugation | PE |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Immunology |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Background: CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
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Journal: LIFE SCIENCES | Year: 2025 | Impact Factor: 5.200
DOI: 10.1016/j.lfs.2025.123713 | Reactivity: Human, Mouse | Sample Type: myeloid-derived suppressor cells (MDSCs) - KDM6B enhances anti-PD-L1 immunotherapy efficacy by increasing CD8+ T-cell infiltration in colorectal cancer
Journal: Journal of Cancer | Year: 2025 | Impact Factor: 3.200
DOI: 10.7150/jca.118571 | Reactivity: Human, Mouse | Sample Type: Human peripheral blood mononuclear cells (PBMCs) - Interleukin-17A facilitates tumor progression via upregulating programmed death ligand-1 expression in hepatocellular carcinoma
Journal: World Journal of Gastrointestinal Oncology | Year: 2025 | Impact Factor: 2.500
DOI: 10.4251/wjgo.v17.i1.97831 | Reactivity: Human, Mouse | Sample Type: Hep3B cell,Huh7 cell,HCCLM3 cell,T cell
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