| Size | Price (USD) |
| 100Tests | $120.00 |
| 50Tests | $78.00 |
| 100Tests×2 | $192.00 |
Product Details
| Abbre | CD107a/LAMP-1 |
| Synonyms | CD107 antigen-like family member Alysosomal membrane glycoprotein 1lysosome-associated membrane protein 1, LAMP-1, Lysosome-associated membrane glycoprotein 1, LAMP-1 |
| Swissprot | P11438 |
| Reactivity | Mouse |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 1D4B |
| Isotype | Rat IgG2a, κ |
| Isotype Control | PE Rat IgG2a, κ Isotype Control[2A3] |
| Applications | FCM |
| Conjugation | PE |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Cellular Localization | Membrane;Cytoplasm |
Product Description
Conjugation Information: PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Background: The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
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