PE/Cyanine5 Anti-Mouse CD49b/pan-NK cells Antibody[DX5] (E-AB-F1116UG) elabscience
$220.00
In stock
SKU
E-AB-F1116UG
| Size | Price (USD) |
| 100μg | $220.00 |
| 25μg | $80.00 |
Product Details
| Abbre | CD49b |
| Synonyms | CD49 antigen-like family member B, CD49b, Collagen receptor, GPIa, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 subunit alpha, pan-NK cells |
| Swissprot | Q62469 |
| Reactivity | Mouse |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | DX5 |
| Isotype | Rat IgM, κ |
| Isotype Control | PE/Cyanine5 Rat IgM, κ Isotype Control[RTK2118] |
| Applications | FCM |
| Conjugation | PE/Cyanine 5 |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Adhesion, Cell Biology, Immunology, Innate Immunity |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: PE/Cyanine5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 670 nm (e.g., a 690/50 nm bandpass filter).
Background: DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
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