PE/Cyanine7 Anti-Human CD45RA Antibody[HI100] (E-AB-F1052H) elabscience

$204.00
In stock
SKU
E-AB-F1052H
SizePrice (USD)
100Tests$204.00
20Tests$90.00
100Tests×2$240.00

Product Details

AbbreCD45RA
SynonymsCD45, L-CA, Ly-5, Ptprc, Receptor-type tyrosine-protein phosphatase C, T200
SwissprotP08575
ReactivityHuman
HostMouse
ClonalityMonoclonal
CloneHI100
IsotypeMouse IgG2b, κ
Isotype ControlPE/Cyanine7 Mouse IgG2b, κ Isotype Control[MPC-11]
ApplicationsFCM
ConjugationPE/Cyanine 7
Concentration5 μL/Test
BufferPhosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research AreasCell Biology, Immunology, Inhibitory Molecules, Neuroscience, Neuroscience Cell Markers
Cellular LocalizationMembrane

Product Description

Conjugation Information: PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter).

Background: CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naïve T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

Storage and Shipping

StorageThis product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze.
ShippingIce bag
  1. CD40 promotes AML survival via non-canonical NF-κB signaling and aberrant lipid metabolism
    Journal: INTERNATIONAL IMMUNOPHARMACOLOGY | Year: 2025 | Impact Factor: 4.800
    DOI: 10.1016/j.intimp.2025.114665 | Reactivity: Human | Sample Type: Kasumi-1 cell

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