APC Anti-Human/Monkey CD20 Antibody[2H7] (E-AB-F1212E) elabscience
$173.00
In stock
SKU
E-AB-F1212E
| Size | Price (USD) |
| 100Tests | $173.00 |
| 20Tests | $72.00 |
| 100Tests×2 | $228.00 |
Product Details
| Abbre | CD20 |
| Synonyms | B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, MS4A1 |
| Swissprot | P11836 |
| Reactivity | Human, Rhesus, Cynomolgus |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 2H7 |
| Isotype | Mouse IgG2b, κ |
| Isotype Control | APC Mouse IgG2b, κ Isotype Control[MPC-11] |
| Applications | FCM |
| Conjugation | APC |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Costimulatory Molecules, Immunology |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Background: CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
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