| Size | Price (USD) |
| 100Tests | $86.00 |
| 50Tests | $55.00 |
| 100Tests×2 | $155.00 |
Product Details
| Abbre | CD122 |
| Synonyms | IL-2R subunit beta, CD122, High affinity IL-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2RB, Il2rb, Interleukin-2 receptor subunit beta, p70-75 |
| Swissprot | P16297 |
| Reactivity | Mouse |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 5H4 |
| Isotype | Rat IgG2a, κ |
| Isotype Control | PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3] |
| Applications | FCM |
| Conjugation | PE/Cyanine 7 |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Immunology |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter).
Background: CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
