| Size | Price (USD) |
| 100Tests | $220.00 |
| 50Tests | $130.00 |
| 100Tests×2 | $330.00 |
Product Details
| Abbre | CD200/OX2 |
| Synonyms | MRC, OX-2, OX-2 membrane glycoprotein |
| Swissprot | O54901 |
| Reactivity | Mouse |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | OX-90 |
| Isotype | Rat IgG2a, κ |
| Isotype Control | PE/Cyanine7 Rat IgG2a, κ Isotype Control[2A3] |
| Applications | FCM |
| Conjugation | PE/Cyanine 7 |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Neuroscience Cell Markers |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter).
Background: CD200 (OX-2 antigen) is a type-1 membrane glycoprotein containing two extracellular Ig-like domains. CD200 a highly conserved type I membrane glycoprotein that is expressed on a variety of cell types including thymocytes, some T cells, endothelial and follicular dendritc cells, B cells, and brain tissue (neurons); but not on NK cells, granulocytes, monocytes, or macrophages. CD200 costimulates T cell proliferation. It may regulate myeloid cell activity in a variety of tissues. CD200 is the ligand for CD200 receptor (CD200R). The CD200 Receptor is restricted to myeloid cells, and it is believed that its engagement with CD200 results in inhibition and/or downregulation of myeloid cell activity. Blocking of CD200/CD200R interactions decreases myeloid cell inhibitory thresholds which results in enhanced immune activation.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
