| Size | Price (USD) |
| 100Tests | $130.00 |
| 20Tests | $52.00 |
| 100Tests×2 | $200.00 |
Product Details
| Abbre | CD45 |
| Synonyms | CD45, L-CA, Ly-5, Ptprc, Receptor-type tyrosine-protein phosphatase C, T200 |
| Swissprot | P08575 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | HI30 |
| Isotype | Mouse IgG1, κ |
| Isotype Control | PE/Elab Fluor ® 594 Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications | FCM |
| Conjugation | PE/Elab Fluor ® 594 |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: PE/Elab Fluor ® 594 is designed to be excited by the blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 620 nm (e.g., a 610/20 nm bandpass filter).
Background: CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
