Product Details
| Abbre | CD3 |
| Synonyms | CD3, CD3E/D/G/Z, CD3e/d/g/z, T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain |
| Swissprot | P04235 P11942 P22646 P24161 |
| Reactivity | Mouse |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 17A2 |
| Isotype | Rat IgG2b, κ |
| Isotype Control | PE/Elab Fluor ® 594 Rat IgG2b, κ Isotype Control[LTF-2] |
| Applications | FCM |
| Conjugation | PE/Elab Fluor ® 594 |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Immunology |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: PE/Elab Fluor ® 594 is designed to be excited by the blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 620 nm (e.g., a 610/20 nm bandpass filter).
Background: CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |