PerCP Anti-Human CD47 Antibody[CC2C6D4] (E-AB-F1060F) elabscience
$285.00
In stock
SKU
E-AB-F1060F
| Size | Price (USD) |
| 100Tests | $285.00 |
| 20Tests | $115.00 |
| 100Tests×2 | $425.00 |
Product Details
| Abbre | CD47 |
| Synonyms | Cd47, IAP, Integrin-associated protein, Leukocyte surface antigen CD47 |
| Swissprot | Q08722 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | CC2C6D4 |
| Isotype | Mouse IgG1, κ |
| Isotype Control | PerCP Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications | FCM |
| Conjugation | PerCP |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Immunology, Innate Immunity |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: PerCP is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter).
Background: CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
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