Purified Anti-Human CD11c Antibody[3.9] (E-AB-F1486A) elabscience
$50.00
In stock
SKU
E-AB-F1486A
| Size | Price (USD) |
| 100μg | $50.00 |
| 25μg | $20.00 |
| Size | Price (USD) |
| 100μg | $50.00 |
| 25μg | $20.00 |
Product Details
| Abbre | CD11c |
| Synonyms | SLEB, Leukocyte adhesion receptor p150+, ITGAX, CD11C, SLEB6, CD11 antigen-like family member C, Integrin alpha-X, Leukocyte adhesion receptor p150+95, p150-95, CR4, integrin &, alpha-X-X |
| Swissprot | P20702 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 3.9 |
| Isotype | Mouse IgG1, κ |
| Applications | FCM |
| Conjugation | Unconjugated |
| Concentration | ≥ 1 mg/mL |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Purification Method | >98%, Protein A/G purified |
| Immunogen | Recombinant Human CD11c protein |
| Research Areas | Signal Transduction, Immunology, Stem Cells |
Product Description
Background: Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.
Storage and Shipping
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Shipping | Ice bag |
Additional Information
| Verified Samples | Verified Samples in FCM: Human peripheral blood granulocytes |
| Dilution | FCM 2 μg/mL(0.5×10^6 -1×10^6 cells) |