Purified Anti-Human CD163 Antibody[GHI/61] (E-AB-F12980P) elabscience

$88.00
In stock
SKU
E-AB-F12980P
SizePrice (USD)
100μg$88.00
25μg$38.00

Product Details

AbbreCD163
SynonymsGHI/, SCARI, CD163, M130, MM130, SCARI1, ED2(rat), GHI/61, Hemoglobin/Haptoglobin Complex Receptor, macrophage-associated antigen, p155, RM3/1, GHI/61
SwissprotQ86VB7
ReactivityHuman
HostMouse
ClonalityMonoclonal
CloneGHI/61
IsotypeMouse IgG1, κ
ApplicationsFCM
ConjugationUnconjugated
Concentration≥ 1 mg/mL
BufferPhosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Purification Method>98%, Protein A/G purified
ImmunogenRecombinant Human CD163 protein
Research AreasImmunology, Cardiovascular

Product Description

Background: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Storage and Shipping

StorageStore at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
ShippingIce bag

Additional Information

Verified SamplesVerified Samples in FCM: Human peripheral blood monocytes
DilutionFCM 2 μg/mL(0.5×10^6 -1×10^6 cells)

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