| Size | Price (USD) |
| 100μg | $88.00 |
| 100mg | $3,214.00 |
| 50mg | $2,236.00 |
| 25mg | $1,338.00 |
| 5mg | $512.00 |
| 1mg | $142.00 |
Product Details
| Abbre | CD45 |
| Synonyms | B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, PTPRC, CD45 antigen, CD45R0, Ly-5, protein tyrosine phosphatase, receptor type, Receptor-type tyrosine-protein phosphatase C, CD45RO, Receptor-type tyrosine-protein phosphatase CLeukocyte common antigen (L-CA), T200, c polypeptide, CD 45, homolog of, Leukocyte common antigen, loc, Lyt-4, OTTHUMP00000033813, OTTHUMP00000033816, OTTHUMP00000033817, OTTHUMP00000038574, Protein tyrosine phosphatase receptor type c polypeptide, protein tyrosine phosphatase, receptor type, C, receptor type C, T200 glycoprotein, T200 leukocyte common antigen, B220, CD45, CD45 antigen, CD45R, GP180, L-CA, LCA, Ly-5, LY5, Protein tyrosine phosphatase, receptor type, Ptprc, Receptor-type tyrosine-protein phosphatase C, T200 |
| Swissprot | P08575 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | BC8 |
| Isotype | Mouse IgG1, κ |
| Applications | FCM |
| Conjugation | None (AF/LE) |
| Concentration | ≥ 1 mg/mL |
| Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Purification Method | >98%, Protein A/G purified |
| Immunogen | Recombinant Human CD45 protein |
| Research Areas | Immunology, Signal Transduction, Neuroscience, Stem Cells, Cardiovascular |
Product Description
Background: CD45, previously called LCA (leukocyte common antigen), T200, or Ly5 in mice, is member C of the class 1 (receptor‑like) protein tyrosine phosphatase family (PTPRC). It is a variably glycosylated 180-220 kDa transmembrane protein that is abundantly expressed on all nucleated cells of hematopoietic origin . Multiple splicing isoforms of exon 4 (A), 5 (B), and 6 (C) are expressed according to cell type, developmental stage and antigenic exposure . The longest form, CD45RABC (called B220 in mouse) is expressed on B lymphocytes, The shortest form, CD45R0, lacking exons 4, 5 and 6 which encode aa 34‑194, is expressed on memory cells, while intermediate sizes are expressed on other T cells.
Storage and Shipping
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice bag |
Additional Information
| Verified Samples | Verified Samples in FCM: Human peripheral blood |
| Dilution | FCM 2 μg/mL(0.5×10^6 -1×10^6 cells) |
