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Purified Anti-Mouse CD120b/TNFR2 Antibody[TR75-54.7] (E-AB-F1035A) elabscience

Purified Anti-Mouse CD120b/TNFR2 Antibody[TR75-54.7] (E-AB-F1035A) elabscience

Name: Purified Anti-Mouse CD120b/TNFR2 Antibody[TR75-54.7] (E-AB-F1035A) elabscience
SKU: E-AB-F1035A
Price: 50 USD
Availability: InStock

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$50.00

In stock

SKU

E-AB-F1035A

Size	Price (USD)
100μg	$50.00
25μg	$20.00

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Product introduction

Product Details

Abbre	CD120b/TNFR2
Synonyms	CD120b, TNF-R2, TNF-RII, TNFR-II, Tnfrsf1b, Tumor necrosis factor receptor 2, Tumor necrosis factor receptor superfamily member 1B, p75, p80 TNF-alpha receptor
Swissprot	P25119
Reactivity	Mouse
Host	Armenian Hamster
Clonality	Monoclonal
Clone	TR75-54.7
Isotype	Armenian Hamster IgG
Applications	FCM
Conjugation	Unconjugated
Concentration	≥ 1 mg/mL
Buffer	Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Research Areas	Immunology, Innate Immunity

Product Description

Background: CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.

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