APC Anti-Mouse CD45 Antibody[30-F11] (E-AB-F1136UE) elabscience
| Size | Price (USD) |
| 100μg | $94.00 |
| 25μg | $33.00 |
| Size | Price (USD) |
| 100μg | $94.00 |
| 25μg | $33.00 |
Product Details
| Abbre | CD45 |
| Synonyms | CD45, L-CA, Ly-5, Ptprc, Receptor-type tyrosine-protein phosphatase C, T200 |
| Swissprot | P06800 |
| Reactivity | Mouse |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | 30-F11 |
| Isotype | Rat IgG2b, κ |
| Isotype Control | APC Rat IgG2b, κ Isotype Control[LTF-2] |
| Applications | FCM |
| Conjugation | APC |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Biology, Immunology, Inhibitory Molecules, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Background: CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |