APC Anti-Mouse CD80 Antibody[16-10A1] (E-AB-F0992E) elabscience
$115.00
In stock
SKU
E-AB-F0992E
100Tests $ 115.00
Product Details
| Abbre | CD80 |
| Synonyms | Activation B7-1 antigen, B7, Cd80, T-lymphocyte activation antigen CD80 |
| Swissprot | Q00609 |
| Reactivity | Mouse |
| Host | Armenian Hamster |
| Clonality | Monoclonal |
| Clone | 16-10A1 |
| Isotype | Armenian Hamster IgG |
| Isotype Control | APC Armenian Hamster IgG Isotype Control[PIP] |
| Applications | FCM |
| Conjugation | APC |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Neuroscience Cell Markers |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Background: CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
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