Biotin Anti-Human/Mouse/Rat CD47 Antibody[MIAP410] (E-AB-F1016B) elabscience
$82.00
In stock
SKU
E-AB-F1016B
| Size | Price (USD) |
| 100μg | $82.00 |
| 25μg | $36.00 |
Product Details
| Abbre | CD47 |
| Synonyms | Cd47, IAP, Integrin-associated protein, Leukocyte surface antigen CD47 |
| Swissprot | Q08722 Q61735 P97829 |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | MIAP410 |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Biotin Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications | FCM |
| Conjugation | Biotin |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Immunology, Innate Immunity |
| Cellular Localization | Membrane |
Product Description
Background: CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Do not freeze. |
| Shipping | Ice bag |
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