Biotin Anti-Mouse CD86 Antibody[GL-1] (E-AB-F0994B) elabscience
$82.00
In stock
SKU
E-AB-F0994B
| Size | Price (USD) |
| 100μg | $82.00 |
| 25μg | $36.00 |
Product Details
| Abbre | CD86 |
| Synonyms | Activation B7-2 antigen, Cd86, ETC-1, Early T-cell costimulatory molecule 1, T-lymphocyte activation antigen CD86 |
| Swissprot | P42082 |
| Reactivity | Mouse |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | GL-1 |
| Isotype | Rat IgG2a, κ |
| Isotype Control | Biotin Rat IgG2a, κ Isotype Control[2A3] |
| Applications | FCM |
| Conjugation | Biotin |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Biology, Costimulatory Molecules, Immunology, Neuroscience, Neuroscience Cell Markers |
| Cellular Localization | Membrane |
Product Description
Background: CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Do not freeze. |
| Shipping | Ice bag |
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