AK2 Polyclonal Antibody (E-AB-10926) elabscience
$399.00
In stock
SKU
E-AB-10926
| Size | Price (USD) |
| 200μL | $399.00 |
| 120μL | $240.00 |
| 60μL | $143.00 |
| 20μL | $73.00 |
Product Details
| Abbre | AK2 |
| Synonyms | mitochondrial, ADK2, AK 2, ATP AMP transphosphorylase, ATP-AMP transphosphorylase 2, Adenylate kinase 2, Adenylate kinase isoenzyme 2, EC 2.7.4.3, KAD2, adenylate kinase 2, ak2, mitochondrial |
| Swissprot | P54819 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | WB, IHC |
| Conjugation | Unconjugated |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Immunogen | Recombinant protein of human AK2 |
| Calculated MW | 26 kDa |
| Research Areas | Cancer, Cell Biology, Metabolism, Signal Transduction |
| Cellular Localization | Mitochondrion intermembrane space. |
Product Description
Background: Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.
Storage and Shipping
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Additional Information
| Verified Samples | Verified Samples in WB: Human placenta, A549, Mouse brain, HepG2, Raji, Human fetal liver, Hela Verified Samples in IHC: Human cervical cancer, Human colon cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
Reviews
Write Your Own Review