ALOX12 Polyclonal Antibody (E-AB-66327) elabscience
$530.00
In stock
SKU
E-AB-66327
| Size | Price (USD) |
| 200μL | $530.00 |
| 120μL | $320.00 |
| 60μL | $200.00 |
Product Details
| Abbre | ALOX12 |
| Synonyms | 12-LOX, 12S-LOX, 12S-type, ALOX12, LOG12 |
| Swissprot | P18054 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | IHC, IF |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Immunogen | Recombinant fusion protein of human ALOX12 (NP_000688.2). |
| Research Areas | Signal Transduction, Cardiovascular, Cancer, Metabolism |
| Cellular Localization | Cytoplasm, Membrane. |
Product Description
Background: This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins. The encoded enzyme and its reaction products have been shown to regulate platelet function. Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients. Allelic variants in this gene may be associated with susceptibility to toxoplasmosis. Multiple pseudogenes of this gene have been identified in the human genome.
Storage and Shipping
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Additional Information
| Verified Samples | Verified Samples in IHC: Rat heart, Human colon carcinoma, Mouse brain Verified Samples in IF: Rat lung |
| Dilution | IHC 1:50-1:200, IF 1:50-1:200 |
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