ATXN1 Polyclonal Antibody (E-AB-10990) elabscience
$399.00
In stock
SKU
E-AB-10990
| Size | Price (USD) |
| 200μL | $399.00 |
| 120μL | $240.00 |
| 60μL | $143.00 |
| 20μL | $73.00 |
Product Details
| Abbre | ATXN1 |
| Synonyms | ATX1, Ataxin-1, Atxn1, D6S504E, OTTHUMP00000016065, SCA1, Spinocerebellar ataxia type 1 protein, alternative ataxin1 |
| Swissprot | P54253 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | IHC |
| Conjugation | Unconjugated |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Immunogen | Recombinant protein of human ATXN1 |
| Research Areas | Epigenetics and Nuclear Signaling, Neuroscience |
| Cellular Localization | Cytoplasm. Nucleus. Colocalizes with USP7 in the nucleus. |
Product Description
Background: The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord.Clinically, ADCA has been divided into three groups: ADCA types I-III.ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes.ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders.Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions.
Storage and Shipping
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Additional Information
| Verified Samples | Verified Samples in IHC: Human thyroid cancer, Human brain |
| Dilution | IHC 1:50-1:200 |
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