| Size | Price (USD) |
| 100Tests | $285.00 |
| 20Tests | $102.00 |
| 100Tests×2 | $425.00 |
Product Details
| Abbre | CD161 |
| Synonyms | NKRP1A, CLEC5B, HNKR-P1a, KLRB1, NKR-P1A |
| Swissprot | Q12918 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | HP-3G10 |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Elab Fluor ® 647 Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications | FCM |
| Conjugation | Elab Fluor ® 647 |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Research Areas | Cell Biology, Immunology, Innate Immunity, Signal Transduction |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: Elab Fluor ® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter).
Background: CD161 is a type II transmembrane glycoprotein, also known as NKR-P1A, that is expressed as a 40-44 kD homodimer. It is a member of the C-type lectin superfamily. CD161 is expressed on a majority of NK cells, NKT cells, and subsets of peripheral T cells and CD3+ thymocytes. It has been reported that Th17 cells are a subpopulation of CD4+CD161+CCR6+ cells. While the biological function of CD161 is not clear, it has been suggested to serve either as a stimulatory receptor or to inhibit NK cell-mediated cytotoxicity and cytokine production. LLT-1 (lectin-like transcript-1, also named as osteoclast inhibitory lectin or CLEC2D) is the ligand of CD161.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
