| Size | Price (USD) |
| 100Tests | $285.00 |
| 20Tests | $120.00 |
| 100Tests×2 | $425.00 |
Product Details
| Abbre | CD244 |
| Swissprot | Q9BZW8 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | C1.7 |
| Isotype | Mouse IgG1, κ |
| Isotype Control | Elab Fluor ® 647 Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications | FCM |
| Conjugation | Elab Fluor ® 647 |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Cellular Localization | Membrane |
Product Description
Conjugation Information: Elab Fluor ® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter).
Background: CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including most CD8+ T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression.
Storage and Shipping
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
