CTRB1 Polyclonal Antibody (E-AB-52723) elabscience
$399.00
In stock
SKU
E-AB-52723
| Size | Price (USD) |
| 200μL | $399.00 |
| 120μL | $240.00 |
| 60μL | $143.00 |
| 20μL | $73.00 |
Product Details
| Abbre | CTRB1 |
| Synonyms | CTRB, CTRB 1, Chymotrypsinogen B, Chymotrypsinogen B1, ChymotrypsinogenB, ChymotrypsinogenB1, FLJ42412, MGC88037, OTTHUMP00000214638 |
| Swissprot | P17538 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Applications | WB, IHC |
| Conjugation | Unconjugated |
| Concentration | 1.02 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Immunogen | Fusion protein of human CTRB1 |
| Calculated MW | 28 kDa |
| Observed MW | Refer to figures The actual band is not consistent with the expectation. Western blotting is a method for detecting a certain protein in a complex sample based on the specific binding of antigen and antibody. Different proteins can be divided into bands based on different mobility rates. The mobility is affected by many factors, which may cause the observed band size to be inconsistent with the expected size. The common factors include: 1. Post-translational modifications: For example, modifications such as glycosylation, phosphorylation, methylation, and acetylation will increase the molecular weight of the protein. 2. Splicing variants: Different expression patterns of various mRNA splicing bodies may produce proteins of different sizes. 3. Post-translational cleavage: Many proteins are first synthesized into precursor proteins and then cleaved to form active forms, such as COL1A1. 4. Relative charge: the composition of amino acids (the proportion of charged amino acids and uncharged amino acids). 5. Formation of multimers: For example, in protein dimer, strong interactions between proteins can cause the bands to be larger. However, the use of reducing conditions can usually avoid the formation of multimers. If a protein in a sample has different modified forms at the same time, multiple bands may be detected on the membrane. |
| Research Areas | Cell Biology |
| Cellular Localization | Secreted, extracellular space. |
Product Description
Background: This gene encodes a member of the serine protease family of enzymes and forms a principal precursor of the pancreatic proteolytic enzymes. The encoded preproprotein is synthesized in the acinar cells of the pancreas and secreted into the small intestine where it undergoes proteolytic activation to generate a functional enzyme. This gene is located adjacent to a related chymotrypsinogen gene. This gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature protein.
Storage and Shipping
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Additional Information
| Verified Samples | Verified Samples in WB: Mouse pancreas, Rat pancreas Verified Samples in IHC: Human cervical cancer |
| Dilution | WB 1:1000-1:5000, IHC 1:20-1:100 |
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