SAM, GMP Grade(Cat. No.:GMP-S062) novoprotein
$50.00
In stock
SKU
GMP-S062
0.5ml: Inquiry
5ml: Inquiry
50ml: Inquiry
Description
S-(5’-Adenosyl)-L-methionine (SAM, AdoMet) with an activating methyl group is the methyl donor for vaccinia capping enzyme (GMP-M062) and mRNA Cap 2’-O-Methyltransferase (GMP-M072) catalyzed methylation, the storage buffer formula is: 0.005M Sulfuric Acid, 10% ETOH.
SAM processes are strictly controlled to ensure the end products free from impurities following the Pharmaceutical Manufacturing Guidelines. We guarantee the manufacturing and quality control comply with GMP regulation for tracking each and every step of the manufacturing process, including raw material sourcing.
This product has passed the HALAL certification.
Quality Control
| Element | Standard |
| Appearance | Clear and transparent solution |
| Visible Particles | Meet the specification |
| Purity | ≥96% |
| Concentration | 32mM±3mM |
| λmax UV absorption peak | 259nm±2nm |
| Endonuclease Residues | The degradation of substrate was ≤10% |
| Exonuclease Residues | The degradation of substrate was ≤10% |
| RNase Residues | The degradation of substrate was ≤10% |
| Microbial Limit | Total aerobic microbial count≤1cfu/10ml, total yeasts and molds count≤1cfu/10ml |
Product Details
| Item | Details |
| Storage | At -20±5℃. |
Components
| SKU | Components | Volume |
| GMP-S062-01A | SAM, GMP Grade | 0.5ml |
| GMP-S062-M005 | SAM, GMP Grade | 5ml |
| GMP-S062-M050 | SAM, GMP Grade | 50ml |
Notes
SAM is unstable at pH 7–8 at 37°C and needs to be freshly prepared before the reaction starts. The amount of SAM can be calculated in advance and the 32 mM stock solution can be diluted to a working solution prior to the start of the reaction. To avoid SAM degradation, this working solution needs to be kept on ice.
Related Products
| Cat. No. | Product Name | Cat. No. | Product Name |
| GMP-M062 | Vaccinia Capping System, GMP Grade | GMP-E125 | RNase Inhibitor, GMP Grade |
| GMP-M072 | mRNA Cap 2´-O-Methyltransferase, GMP Grade | GMP-E127 | DNase I, GMP Grade |
| GMP-M012 | E. coli Poly(A) Polymerase, GMP Grade | GMP-M036 | Pyrophosphatase, Inorganic (yeast), GMP Grade |
| GMP-E121 | T7 RNA Polymerase,GMP Grade | GMP-S023-026 | NTPs, GMP Grade |
title: Deciphering the Mechanism: Overcoming Incompatibility for Continuous Cap-1 mRNA Synthesis via Multienzyme Cascades
authors: Shiyi Che, Zhengjun Li, Zhiguo Su, Aibing Yu, Minsu Liu, Songping Zhang
date: 2026/03/12
journal: ACS Sustainable Chemistry & Engineering
title: Engineering of BZ transposase and transposon donor vector for enhanced efficiency and safety in gene delivery applications
authors: Wang Saisai, Zhang Pingjing, Sun Yan, Fang Yuan, Wang Pei, Shao Meiqi, Zhang Ningning, Shi Shasha, Chen Xin, Gao Haixia, Cheng Jingbo, Gao Bo, Liu Tao, Qian Qijun, Song Chengyi
date: 2025/09/23
journal: NUCLEIC ACIDS RESEARCH
title: On-column capping of poly dT media-tethered mRNA accomplishes high capping efficiency, enhanced mRNA recovery, and improved stability against RNase
authors: Shiyi Che, Xue Feng, Zhengjun Li, Zhiguo Su, Guanghui Ma, Zhikao Li, Aibing Yu, Minsu Liu, Songping Zhang
date: 2023-09-25
journal: BIOTECHNOLOGY AND BIOENGINEERING
MDSD
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
