Recombinant Human ANXA2(Cat. No.:C205) novoprotein
$105.00
In stock
SKU
C205
10μg: $105
50μg: $315
500μg: $1540
1mg: $2200
Description
Recombinant Human Annexin A2 is produced by our E.coli expression system and the target gene encoding Ser2-Asp339 is expressed.
Product Details
| Item | Details |
| Known As | Annexin A2; Annexin II; Annexin-2; Calpactin I Heavy Chain; Calpactin-1 Heavy Chain; Chromobindin-8; Lipocortin II; Placental Anticoagulant Protein IV; PAP-IV; Protein I; p36; ANXA2; ANX2; ANX2L4; CAL1H; LPC2D |
| Mol Mass | 38.6 KDa |
| APMol Mass | 35 KDa, reducing conditions |
| Formulation Description | Lyophilized from a 0.2 μm filtered solution of 20mM Histidine-HCl, 6% Sucrose, 4% Mannitol, 0.05%Tween 80, pH 5.5. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Storage | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Background
Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein is associated with sickle cell osteonecrosis and the expression reduce of ANXA2 is associated with osteosarcoma metastases. ANXA2 functions as an autocrine factor, it can increases osteoclast formation and bone resorption. ANXA2 is involved in muscular dystrophies. In humans, the up-regulation of ANXA2 is related with colon adenocarcinoma cell differentiation.
title: Human epididymis protein 4 promotes P‑glycoprotein‑mediated chemoresistance in ovarian cancer cells through interactions with Annexin II
authors: Qing Liu, Da-Wo Liu, Ming-Jun Zheng, Lu Deng, Hui-Min Wang, Shan Jin, Juan-Juan Liu, Ying-Ying Hao, Lian-Cheng Zhu, Bei Lin
date: 2021
journal: Molecular Medicine Reports
title: Annexin A2 is a target of autoimmune T and B cell responses associated with synovial fibroblast proliferation in patients with antibiotic-refractory Lyme arthritis
authors: Annalisa Pianta, Elise E. Drouin, Jameson T. Crowley, Sheila Arvikar, Klemen Strle, Catherine E. Costello, Allen C. Steere
date: 2015
journal: CLINICAL IMMUNOLOGY
title: Influenza Virus Infection Elicits Protective Antibodies and T Cells Specific for Host Cell Antigens Also Expressed as Tumor-Associated Antigens: A New View of Cancer Immunosurveillance
authors: Iheagwara Uzoma K., Beatty Pamela L., Van Phu T., Ross Ted M., Minden Jonathan S., Finn Olivera J.
date: 2014
journal: Cancer Immunology Research
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