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Recombinant Mouse CD38 (C-Fc)(Cat. No.:CU98) novoprotein

Recombinant Mouse CD38 (C-Fc)(Cat. No.:CU98) novoprotein

Name: Recombinant Mouse CD38 (C-Fc)(Cat. No.:CU98) novoprotein
SKU: CU98
Price: 50 USD
Availability: InStock

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$50.00

In stock

SKU

CU98

10μg: $50 50μg: $150 500μg: $750 1mg: $1100

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Description

Recombinant Mouse ADP-ribosyl Cyclase/cyclic ADP-ribose Hydrolase 1 is produced by our Mammalian expression system and the target gene encoding Leu45-Thr304 is expressed with a human IgG1 Fc tag at the C-terminus.

Product Details

Item	Details
Known As	ADP-ribosyl cyclase 1; cyclic ADP-ribose hydrolase;CD38;T10
Mol Mass	56.9 KDa
APMol Mass	70-90 KDa, reducing conditions
Formulation Description	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.
Endotoxin	< 1 EU/µg as determined by LAL test.
Reconstitution	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage	Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Background

CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. And also moonlights as a receptor in cells of the immune system. CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.