Recombinant Human OSM(Cat. No.:GMP-C099) novoprotein

$50.00
In stock
SKU
GMP-C099
50μg: Inquiry 500μg: Inquiry 1mg: Inquiry

Description

Recombinant human tumor suppressor M (OSM) is a glycoprotein belonging to the IL-6 cytokine family, which can inhibit the proliferation of various tumor cells and induce the differentiation of certain tumor cells. OSM can promote the differentiation of embryonic stem cells (ESCs) and induce the differentiation of pluripotent stem cells (iPSCs). OSM is also involved in many biological metabolic processes, including liver development, hematopoiesis, inflammation, bone formation, and destruction.

Recombinant Human OSM is expressed by E.Coli, and is produced with raw materials of pharmaceutical applicable level. The host protein residue, nucleic acid residue and common pathogens are strictly controlled, and the production and quality management procedures of the product comply with GMP regulations to ensure the traceability of the production process and all raw materials.

Usage

In-vitro cultivation of various types of cell.

Quality Control

ItemStandard
AppearanceSolidoid, white porosity
ReconstitutionTotally dissolve in stated time
Visible particleConform to ChP
pH value7.0-8.0
Purity≥ 95%,SDS-PAGE;≥ 92%,SEC-HPLC
Bioactivity≥ 1.0×10<sup>6</sup> IU/mg
Endotoxin< 10 EU/mg
Host protein≤ 0.005%
Exogenous DNA residue≤ 10 ng/mg
Mycoplasma testNegative
Sterility testConform to ChP

Product Details

ItemDetails
StorageStorage at -20±5 ℃, expiration date labeled on bottle.
Recommendations(1)Make sure the product properly stored and none expired before using.
(2)Please use water for injection for reconstitution, to a concentration > 100 μg/ml.
(3)Sterile condition without pyrogen is required for reconstitution, re-aliquoting, dilution.
(4)After reconstitution, aliquoted solution vials should be stored at -70°C and minimize freeze-thaw cycles preventing denaturation of protein.

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authors: Zhou Xiangnan, Ning Jingyuan, Wu Doudou, Liu Qingwu, Jiang Wenbo, Liu Jiayi, Cai Rui, Liu Diangang, Bai Yanping
date: 2025/05/22
journal: MOLECULAR MEDICINE

title: Inhibition of CTSC contributes to psoriasis inflammation and keratinocyte hyperproliferation by NF-κB signaling pathway
authors: Yue He, Maoxin Huang, Yu Wang, Xinying Cai, Fengli Xiao
date: 2025/05/07
journal: INTERNATIONAL IMMUNOPHARMACOLOGY

title: Oncostatin M induces IFITM1 expression to inhibit hepatitis B virus replication via JAK-STAT signaling
authors: Yuchen Ye, Ya Fu, Caorui Lin, Ye Shen, Qingqing Yu, Xiaobao Yao, Qunfang Huang, Can Liu, Yongbin Zeng, Tianbin Chen, Songhang Wu, Zhen Xun, Qishui Ou
date: 2023-10-23
journal: Cellular and Molecular Gastroenterology and Hepatology

MDSD

Datasheet

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