Description
Recombinant human tumor suppressor M (OSM) is a glycoprotein belonging to the IL-6 cytokine family, which can inhibit the proliferation of various tumor cells and induce the differentiation of certain tumor cells. OSM can promote the differentiation of embryonic stem cells (ESCs) and induce the differentiation of pluripotent stem cells (iPSCs). OSM is also involved in many biological metabolic processes, including liver development, hematopoiesis, inflammation, bone formation, and destruction.
Recombinant Human OSM is expressed by E.Coli, and is produced with raw materials of pharmaceutical applicable level. The host protein residue, nucleic acid residue and common pathogens are strictly controlled, and the production and quality management procedures of the product comply with GMP regulations to ensure the traceability of the production process and all raw materials.
Usage
In-vitro cultivation of various types of cell.
Quality Control
| Item | Standard |
| Appearance | Solidoid, white porosity |
| Reconstitution | Totally dissolve in stated time |
| Visible particle | Conform to ChP |
| pH value | 7.0-8.0 |
| Purity | ≥ 95%,SDS-PAGE;≥ 92%,SEC-HPLC |
| Bioactivity | ≥ 1.0×10<sup>6</sup> IU/mg |
| Endotoxin | < 10 EU/mg |
| Host protein | ≤ 0.005% |
| Exogenous DNA residue | ≤ 10 ng/mg |
| Mycoplasma test | Negative |
| Sterility test | Conform to ChP |
Product Details
| Item | Details |
| Storage | Storage at -20±5 ℃, expiration date labeled on bottle. |
| Recommendations | (1)Make sure the product properly stored and none expired before using. (2)Please use water for injection for reconstitution, to a concentration > 100 μg/ml. (3)Sterile condition without pyrogen is required for reconstitution, re-aliquoting, dilution. (4)After reconstitution, aliquoted solution vials should be stored at -70°C and minimize freeze-thaw cycles preventing denaturation of protein. |
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