Recombinant Human sCD40 Ligand(Cat. No.:GMP-CI56) novoprotein
$50.00
In stock
SKU
GMP-CI56
50μg: Inquiry
500μg: Inquiry
1mg: Inquiry
Description
CD40L, also known as CD154, is a plasma membrane glycoprotein and differentiation antigen expressed on the surface of T cells. It stimulates the proliferation of B cells to secrete various immunoglobulins in the presence of cytokines. CD40L can induce the cytokines secretion of peripheral blood mononuclear cells, so produce anti-tumor activity. It also has a co-stimulatory effect on the proliferation of activated T cells, accompanied by the production of IFN-gamma, TNF-alpha, and IL-2.
Recombinant Human sCD40L is expressed by mammalian cells, and is produced with raw materials of pharmaceutical applicable level. The host protein residue, nucleic acid residue and common pathogens are strictly controlled, and the production and quality management procedures of the product comply with GMP regulations to ensure the traceability of the production process and all raw materials.
Usage
In-vitro cultivation of various types of cells.
Quality Control
| Item | Standard |
| Appearance | White porosity/white powder |
| Reconstitution | Totally dissolve in stated time |
| Visible particle | Conform to ChP |
| pH value | 6.5–7.5 |
| Purity | ≥ 95%, SDS-PAGE&SEC-HPLC |
| Bioactivity | ≤ 10 ng/ml |
| Endotoxin | < 10 EU/mg |
| Host protein | ≤ 0.005% |
| Exogenous DNA residue | ≤ 100 pg/mg |
| Mycoplasma test | Negative |
| Sterility test | Conform to ChP |
Product Details
| Item | Details |
| Storage | Storage at -20±5℃, expiration date labeled on bottle. |
| Recommendations | （1）Make sure the product properly stored and none expired before using. （2）Please use water for injection for reconstitution, to a concentration > 100 μg/ml. （3）Sterile condition without pyrogen is required for reconstitution, re-aliquoting, dilution. （4）After reconstitution, aliquoted solution vials should be stored at -70°C and minimize freeze-thaw cycles preventing denaturation of protein. |
MDSD
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