Description
Recombinant Cynomolgus Interleukin-13 is produced by our Mammalian expression system and the target gene encoding Ser19-Asn132 is expressed with a 6His tag at C-terminus.
Product Details
| Item | Details |
| Known As | Interleukin-13; IL-13; T-Cell Activation Protein P600; Il13; Il-13 |
| Mol Mass | 13.3 KDa |
| APMol Mass | 20-38 KDa, reducing conditions |
| Formulation Description | Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Storage | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Background
Interleukin-13 is also known as IL-13. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.
MDSD