Recombinant Mouse/Rat TGF-beta 2(Cat. No.:CK35) novoprotein
$150.00
In stock
SKU
CK35
10μg: $150
50μg: $440
500μg: $1906
1mg: $3050
Description
Recombinant Mouse/Rat Transforming Growth Factor Beta 2 is produced by our Mammalian expression system and the target gene encoding Ala303-Ser414 is expressed.
Product Details
| Item | Details |
| Known As | TGFB2; BSC-1 cell growth inhibitor; Cetermin; Glioblastoma-derived T-cell suppressor factor; G-TSF; MGC116892; Polyergin; TGF-beta2; TGF-beta-2; transforming growth factor beta-2 |
| Mol Mass | 12.7 KDa |
| APMol Mass | 12 KDa, reducing conditions |
| Formulation Description | Lyophilized from a 0.2 μm filtered solution of 4mM HCl. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in 4mM HCl. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Storage | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Background
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-β expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.
title: Integrating spatial transcriptomics and single-nucleus RNA-seq revealed the specific inhibitory effects of TGF-β on intramuscular fat deposition
authors: Wang Xiaoyu, Chen Chuchu, Li Chenggan, Chen Xiaochang, Xu Rong, Chen Meilin, Li Yongpeng, Liu Yihao, Liu Xiaohong, Chen Yaosheng, Mo Delin
date: 2024/10/12
journal: Science China-Life Sciences
MDSD
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