Recombinant Human IGF-II(Cat. No.:CF61) novoprotein

$90.00
In stock
SKU
CF61
10μg: $90 50μg: $250 500μg: $1050 1mg: $1600

Description

Recombinant Human Long Insulin-Like Growth Factor II is produced by our E.coli expression system and the target gene encoding Ala25-Glu91 is expressed.

Product Details

ItemDetails
Known AsInsulin-Like Growth Factor II; IGF-II; Somatomedin-A; IGF2; PP1446
Mol Mass8.91 KDa
APMol Mass11 KDa, reducing conditions
Formulation DescriptionLyophilized from a 0.2 μm filtered solution of 20mM Glycine-HCl, 4% Sucrose, 4% Mannitol, 0.02% Tween 80 (w/v), pH3.0.
Endotoxin< 1 EU/µg as determined by LAL test.
ReconstitutionAlways centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
StorageLyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
ShippingThe product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.

Background

Insulin-Like Growth Factor II (IGF2) belongs to the insulin family of polypeptide growth factors that is involved in development and growth. Members of this family are structurally homologous to proinsulin, and share higher sequence identity. IGF2 is expressed only from the paternally inherited allele and believed to be secreted by the liver and to circulate in the blood. IGF2 possess growth-promoting activity and can stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGF2 is influenced by placental lactogen and may play a role in fetal development.

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